服務(wù)熱線(xiàn)
400-021-2200
| 品牌 | StemRD/美國(guó) |
|---|
StemRD GDC-0449, SMO antagonist 拮抗劑 產(chǎn)品英文簡(jiǎn)述:
GDC-0449 （Vismodegib）: A potent antagonist of SMO （smoothened）. This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molecule has been developed by Genentech for clinical application against hedgehog-dependent cancers.
Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives IC50 of 5-20 nM.
重慶市華雅干細(xì)胞技術(shù)有限公司